Causes of Mesothelioma – An Insight Into the Likely Causes of Mesothelioma

September 2, 2010

Mesothelioma is a very aggressive and rare cancer that is difficult to diagnose and that is also highly resistant to treatment. Around 2000-3000 new cases of malignant mesothelioma are seen every year in the US, and these figures are expected to rise over the next decade.

What causes mesothelioma?

There is extensive and undeniable medical evidence that mesothelioma is caused by exposure to asbestos fibers. There is no other known cause.

Asbestos is a naturally occurring fibrous material that was widely used in industrial, commercial and domestic products throughout the 20th century. It was particularly popular because of its durability, fire resistant and insulating properties. It was used in several thousand different manufactured asbestos products.

These included construction materials, household appliances and brake linings, the use was so widespread that millions of Americans were unknowingly exposed to the toxic material, which now leads to the development of mesothelioma amongst million of Americans.

Most of the companies that manufactured these asbestos contaminated products were aware of the danger of asbestos, but still preferred to put millions at risk to make huge profits.

However today, as more cases are being diagnosed and they are seeking for legal compensation, these companies are being ordered to pay compensations to patients affected by asbestos.

How does asbestos cause mesothelioma?

Internal organs and body cavities are lined by a thin tissue called mesothelium. This lining lines the lungs {pleura} and it also lines the heart sac {pericardium} and abdominal cavity {peritoneum}.

This mesothelial tissue offers protection and support for the internal organs and body cavities. It also provides lubrication to help organ function properly and be in good health.

Mesothelioma affects this lining of various organs and body cavities, mostly the pleura, pericardium, and peritoneum. Occasionally and rarely, the cancer may affect the lining of the testicles, called the tunica vaginalis.

Although the actual mechanism by which asbestos causes cancer is not known, there are about four different theories to explain this:

1-Asbestos causes irritation and inflammation of mesothelial cells, which results in irreversible scarring, cellular damage, and eventually cancer

2- Asbestos fibers enter cells and disrupt the function of cellular structures that are essential for normal cell division, causing cellular changes that lead to cancer.

3-Asbestos causes the production of free radicals. These molecules damage DNA, and cause cells to mutate and become cancerous.

4-The presence of asbestos causes cells to produce oncoproteins. These molecules cause mesothelial cells to ignore normal cellular division restraints, and this can lead to the development of cancer.

The common underlying pathophysiology in each of these theories is that asbestos cause’s cellular damage mainly by causing the cells of the mesothelium to divide and multiply without restraint causing the formation of tumors. This uncontrolled division causes impairment of the normal function of the body organs and tissues.

Does Mesothelioma have other causes?

Although research and medical evidence has not been able to directly prove any other cause of mesothelioma other than asbestos exposure, it is known however that smoking can aggravate a less serious asbestos related disease, such as asbestosis, and prompt formation of tumors and the onset of the cancer.

Also asbestos exposure and smoking have a synergistic effect that increases the risk of developing lung cancer by as much as 84 times or more. Thus people that have been exposed to asbestos for a prolonged period of time are advised to not to smoke.

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Asbestos Litigation: Costs and Compensation

September 1, 2010

Asbestos Litigation: Costs and Compensation

Asbestos Litigation: Costs and Compensation Feature

Asbestos Litigation: Costs and Compensation Overview

The authors analyze the costs and compensation paid for asbestos personal-injury claims, and discuss such issues as the current state of asbestos litigation in the United States, the costs of compensation, the effects of litigation on businesses, and the evolving character of litigation.

Asbestos Litigation: Costs and Compensation Specifications

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Asbestos-Linked Lung Cancer

August 28, 2010

Exposure to asbestos in the place of work, mainly in shipyards, has long been known as a risk factor for mesothelioma, an uncommon kind of cancer having an effect on the lining of the lung. However in the new study, researchers discovered a consistent and dose-dependent connection between mesothelioma and residential proximity to ultramafic rock, the main source of naturally occurring asbestos.

To place the mesothelioma risk in perspective, the illness is in charge for about the same number of lung cancer deaths yearly as passive smoking. According to National Institute of Occupational Safety and Health statistics, in the United States approximately 2,500 people a year die from mesothelioma. According to U.S. Environmental Protection Agency statistics, approximately 3,000 deaths from the disease are attributed to exposure to secondhand tobacco smoke yearly.

Asbestos-linked lung disease arose at very high rates toward the middle of the 20th century, when sufferers who were exposed decades earlier to asbestos ultimately developed disease. British asbestos workers were amongst the first who were detected to suffer lung cancer linked to asbestos. A dose-response association subsists both for the degree of asbestos exposure and the sum of cigarette smoking.

The risk of the cancer and mesothelioma raises with the amount of fibers inhaled. Though the majority asbestos-linked cancers are related to the intensity and duration of exposure, reports in medical journals have connected a number of mesotheliomas to short exposure periods, on the order of months.

Cigarette smoking leads to nearly all lung cancers, but long-term exposure to asbestos is a cause of the disease as well. However, individuals who smoke and have been exposed to asbestos have a very high risk of expanding the disease.

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Estimating Future Claims: Case Studies from Mass Tort and Product Liability

August 25, 2010

Estimating Future Claims: Case Studies from Mass Tort and Product Liability

Estimating Future Claims: Case Studies from Mass Tort and Product Liability Feature

Estimating Future Claims: Case Studies from Mass Tort and Product Liability Overview

This book provides a study of past, present and emerging mass torts with practical information drawn from examples such as asbestos. A must read for plaintiff and defense attorneys, judges, insurance and reinsurance company claims managers, risk managers, brokers, actuarials and executives, this book will help them:

- Identify key data and assumptions necessary at each stage of the estimation process;

- Learn how the incidence and prevalence of a condition is converted into claims;

- Forecast liability exposure for risk management and conveyance of assets;

- Assess reserve and settlement trusts for financial planning and company insulation; and

- Review historical and new estimation techniques.

Estimating Future Claims: Case Studies from Mass Tort and Product Liability Specifications

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Brent Coon – Asbestos/Mesothelioma – Length of Lawsuit

August 21, 2010
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